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International Standards for Cytogenomic Arrays Consortium, NAT, PCR, ISO, NIH

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Month: May 2025

Quantifying Argininosuccinate Synthase in Cell Lysates: ELISA-Based Approach for Metabolic Pathway Studies

By Lieven May 27, 2025

Understanding the functional dynamics of enzymes in cellular systems is key to studying metabolic pathways. One such enzyme, Argininosuccinate Synthase 1 (ASS1), is a central component of the urea cycle, […]

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Implementing External Quality Assessment (EQA) Programs for PCR-Based Diagnostic Laboratories

By Lieven May 26, 2025

Polymerase Chain Reaction (PCR) technology has revolutionized molecular diagnostics by enabling the rapid and sensitive detection of nucleic acids from pathogens, genetic variants, and biomarkers. The precision of PCR testing, […]

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Multiplex Rapid Diagnostic Tests in Veterinary Medicine: Simultaneous Detection of Multiple Pathogens in Companion Animals

By Lieven May 26, 2025

Introduction The field of veterinary diagnostics has seen considerable progress with the advent of multiplex rapid diagnostic tests (RDTs), especially for companion animals such as dogs, cats, rabbits, and exotic […]

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Application of TB-Feron Antigen ELISA in Monitoring Immune Response During Tuberculosis Treatment

By Lieven May 26, 2025

Tuberculosis (TB) caused by Mycobacterium tuberculosis continues to be a significant public health concern worldwide. Monitoring the immune response during TB treatment is critical to evaluate treatment efficacy and to […]

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Applying ErbB3 ELISA in Drug Development: Monitoring Receptor Modulation in Response to Targeted Therapies

By Lieven May 26, 2025

The ErbB3 receptor (HER3) is a significant component of the ErbB family of receptor tyrosine kinases, playing a central role in cell signaling pathways that regulate cell proliferation, differentiation, and […]

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Using AOX1 ELISA Kits for High-Throughput Screening of Enzyme Inhibitors in Xenobiotic Studies

By Lieven May 26, 2025

Introduction Aldehyde oxidase 1 (AOX1) is a molybdenum-containing enzyme that plays a key role in the oxidative metabolism of heterocyclic and aromatic aldehydes, including many compounds classified as xenobiotics. Xenobiotics, […]

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Evaluating the Role of BF ELISA Kits in Preclinical Research and Biomarker Validation

By Lieven May 21, 2025

Introduction Preclinical research plays a crucial role in understanding biological mechanisms and developing novel therapeutic strategies. Accurate measurement and validation of biomarkers are foundational to these efforts. Enzyme-Linked Immunosorbent Assay […]

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Comparative Analysis of ATP6V0C Antibodies for Diagnostic Biomarker Discovery in Cancer and Neurodegenerative Diseases

By Lieven May 20, 2025

Introduction The vacuolar ATPase subunit ATP6V0C is an essential component of the proton pump responsible for acidifying intracellular organelles. This acidification plays a vital role in several cellular processes including […]

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Optimizing Monoclonal Antibody Kits for High-Specificity Diagnostic Applications

By Lieven May 20, 2025

Monoclonal antibody (mAb) kits are pivotal in modern diagnostics, providing tools for sensitive and selective detection of biomolecules. Their high specificity and affinity enable accurate identification of target antigens in […]

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Exploring Drug Modulation of NF-kB Signaling Using the Luciferase Reporter-Jurkat Cell Line

By Lieven May 14, 2025

NF-kB (Nuclear Factor kappa-light-chain-enhancer of activated B cells) is a transcription factor central to regulating numerous cellular processes, such as inflammation, immune response, cell proliferation, and apoptosis. The dysregulation of […]

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